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Updated: Mar 6, 2026

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
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Published on: May 22, 2018

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Aβ 自己組み立ての調節剤としてのα-ヘリックスミメティック

Sunil Kumar1, Andrew D Hamilton1

  • 1Department of Chemistry, New York University , New York, New York 10003, United States.

Journal of the American Chemical Society
|March 9, 2017
PubMed
まとめ

新しい化合物であるADH-41は,アルツハイマー病 (AD) のアミロイドβ (Aβ) 線維と神経毒性オリゴマーの形成を効果的に防ぐ. このα-ヘリクルの模倣は特にAβを標的とし,ADの有望な治療戦略を提供します.

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