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Updated: Mar 6, 2026

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T細胞共刺激受容体CD28は,PD-1媒介による抑制の主な標的である

Enfu Hui1, Jeanne Cheung2, Jing Zhu2

  • 1Department of Cellular and Molecular Pharmacology and the Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA.

Science (New York, N.Y.)
|March 11, 2017
PubMed
まとめ

プログラム細胞死-1 (PD-1) は,T細胞受容体 (TCR) ではなく,CD28共受容体 (CD28) を脱酸化することによって,T細胞活性化を抑制する. これはPD-1を明らかにします.

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