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Updated: Mar 6, 2026

Transduction and Expansion of Primary T Cells in Nine Days with Maintenance of Central Memory Phenotype
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早期の抗体治療は,SHIVに対する長期間続く免疫を誘発する

Yoshiaki Nishimura1, Rajeev Gautam1, Tae-Wook Chun2

  • 1Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Nature
|March 15, 2017
PubMed
まとめ

マカクの早期受動免疫療法により,広範な中和抗体 (bNAbs) が投与され,耐久性の高い感染制御が可能になりました. このアプローチはT細胞免疫を確立し,抗レトロウイルス併用療法とは異なり,猿/ヒト免疫不全ウイルス (SHIV) の長期抑制を可能にしました.

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