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spiroisoxazoline SMARt-420によるMycobacterium tuberculosisにおける抗生物質耐性の回復

Nicolas Blondiaux1, Martin Moune1, Matthieu Desroses2,3

  • 1Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR8204-CIIL-Center for Infection and Immunity of Lille, F-59000 Lille, France.

Science (New York, N.Y.)
|March 18, 2017
PubMed
まとめ

研究者は新しい分子である SMARt-420 を開発し 結核の抗生物質耐性に対抗しました この小さな分子 (SMARt-420) は,眠っている経路を再活性化し,エチオナミドに対する耐性を克服し,マウスの感染を排除します.

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