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Updated: May 3, 2026

Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy
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グリオマ由来のPDGFAチェーンホモジマーは,ヒトの血小板から浄化されたPDGFABヘテロジマとは異なる機能的活動を有する

M Nistér1, A Hammacher, K Mellström

  • 1Department of Pathology, University Hospital, Uppsala, Sweden.

Cell
|March 25, 1988
PubMed
まとめ

グリオマ誘発成長因子I (GDGF-I) と血小板誘発成長因子 (PDGF) は,似たような受容体と結合するが,異なる機能的活動を示す. これらの差異は,異なる成長因子が,細胞シグナル伝達のためのユニークな受容体相互作用を利用する可能性があることを示唆しています.

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