Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Long-Term Memory01:18

Long-Term Memory

791
Long-term memory is a relatively permanent type of memory, capable of storing vast amounts of information over extended periods. Its storage capacity is generally considered unlimited.
Long-term memory can be categorized into two primary types: explicit and implicit memory. Explicit memory, also known as declarative memory, involves the conscious recollection of information that we deliberately try to remember, recall, and articulate. This type of memory encompasses specific facts, events, and...
791
Long-term Potentiation01:35

Long-term Potentiation

59.1K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
59.1K
Long-term Potentiation01:25

Long-term Potentiation

3.7K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
3.7K
Higher Mental Functions of Brain: Learning and Memory01:26

Higher Mental Functions of Brain: Learning and Memory

2.2K
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
2.2K
Associative Learning01:27

Associative Learning

1.6K
Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
1.6K
Long-term Depression01:03

Long-term Depression

3.5K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.5K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Mice produce interneurons in the septum as a response to aversive experiences and antidepressant treatment.

Science advances·2026
Same author

Prefrontal gamma oscillations engage dynamic cell-type-specific configurations to support flexible behavior.

Neuron·2026
Same author

AI-based mouse behavior analysis in pathology: A focus on movement disorders.

Neuroscience and biobehavioral reviews·2026
Same author

PinkyCaMP: an mScarlet-based calcium sensor with enhanced brightness, photostability and multiplexing capabilities.

Nature methods·2026
Same author

The Cooperative Network Architecture: Learning Structured Networks as Representation of Sensory Patterns.

Neural computation·2026
Same author

Prefrontal neural geometry of learned cues guides motivated behaviours.

Nature·2026
Same journal

Six ways to put the public at the heart of science and policy.

Nature·2026
Same journal

The complex truth about trust in science.

Nature·2026
Same journal

Have people stopped trusting science? The data tell a surprising story.

Nature·2026
Same journal

How FAIR data are helping to build trust in science.

Nature·2026
Same journal

Scientists should recognize their own political biases to build public trust.

Nature·2026
Same journal

Harmonizing standards and resources for the medical genome.

Nature·2026
関連記事をすべて見る

関連する実験動画

Updated: Mar 5, 2026

Aversive Associative Learning and Memory Formation by Pairing Two Chemicals in Caenorhabditis elegans
07:17

Aversive Associative Learning and Memory Formation by Pairing Two Chemicals in Caenorhabditis elegans

Published on: June 23, 2022

3.0K

長期連想記憶の基礎となる神経集合のダイナミクス

Benjamin F Grewe1,2,3, Jan Gründemann4, Lacey J Kitch1,2,3

  • 1James H. Clark Center for Biomedical Engineering &Sciences, Stanford University, Stanford, California, USA.

Nature
|March 23, 2017
PubMed
まとめ
この要約は機械生成です。

ニューラル・アンサンブルが 刺激の関連性を学びます この脳の可塑性は 神経の表現を再構成します これは記憶形成と 行動条件を予測するのに 極めて重要です

さらに関連する動画

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

6.0K
Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
14:27

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Published on: August 11, 2019

13.5K

関連する実験動画

Last Updated: Mar 5, 2026

Aversive Associative Learning and Memory Formation by Pairing Two Chemicals in Caenorhabditis elegans
07:17

Aversive Associative Learning and Memory Formation by Pairing Two Chemicals in Caenorhabditis elegans

Published on: June 23, 2022

3.0K
Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

6.0K
Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
14:27

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Published on: August 11, 2019

13.5K

科学分野:

  • 神経科学
  • 認知科学
  • 記憶に関する研究

背景:

  • アソシエティブ・ラーニングは 記憶の基本です
  • アソシエティブメモリエンコーディングの 背後にある神経メカニズムは まだ不明です
  • アミグダラは 恐怖と記憶の形成に 重要な役割を果たします

研究 の 目的:

  • 条件付き刺激 (CS) と無条件刺激 (US) の間の関連をコードする amigdala のニューラルアンサンブルを調査する.
  • 恐怖の学習と絶滅の過程における ニューロンの可塑性のダイナミクスを研究する

主な方法:

  • ミニチュア光顕微鏡を用いて,マウスの桃体ニューロン組のCa2+動態を追跡した.
  • 6日間の恐怖条件付けと絶滅の際に 神経活動を監視した.
  • 行動コンディショニングの強さと相関する神経アンサンブル活動

主要な成果:

  • 恐怖条件付けは 双方向的な可塑性を誘発します
  • CSのニューラルアンサンブル表現は,コンディショニング後のUS表現に類似するようになった.
  • 絶滅訓練は,ベースラインに戻ることなく,CS表現の特異性を高めました.
  • CSとUSの結合の強さは 行動条件を予測した

結論:

  • アミグダラ細胞は 協同学習の過程で 神経表現を動的に再構成します
  • 関連記憶のための監督学習モデルを 支持しています
  • ニューラル・アンサンブルにおける双方向的な可塑性は,CS-US関連をコードする重要なメカニズムである.