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セリアック病のスクリーニング:米国予防サービスタスクフォースの勧告声明

, Kirsten Bibbins-Domingo1, David C Grossman2

  • 1University of California, San Francisco.

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|March 29, 2017
PubMed
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症状のない個体でのセリアック病のスクリーニングを推奨するには,現在の証拠は不十分です. 米国予防サービスタスクフォース (USPSTF) は,スクリーニングの正確性,利益,害に関するデータが不十分であることが判明しました.

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科学分野:

  • 胃腸内科
  • 予防医学
  • 臨床スクリーニング

背景:

  • 遺伝的に敏感な個体でグルテンによって引き起こされる自己免疫疾患です.
  • グルテン摂取は小腸の炎症を誘発する.

研究 の 目的:

  • 米国予防サービスタスクフォース (USPSTF) のセリアック病のスクリーニングに関する勧告を更新する.
  • 無症状の成人,青少年,子供のスクリーニングのための証拠を評価する.

主な方法:

  • スクリーニングの精度に関する証拠の体系的なレビュー
  • スクリーニングと無スクリーニングの利益と害の評価
  • 検査で検出されたセリアック病の治療効果の評価

主要な成果:

  • セリアック病のスクリーニングテストの正確性に関する不十分な証拠が見つかりました.
  • スクリーニング戦略の利益と害に関するデータは不十分です (ターゲットと普遍).
  • 検診で検出されたセリアック病の治療の利益と害に関する証拠は限られている.

結論:

  • USPSTFは,無症状の集団におけるセリアック病のスクリーニングの利益と害のバランスを決定するのに十分な証拠がないと結論付けました.
  • スクリーニングの勧告を基にさらなる研究が必要である.