ヒトパピローマウイルス16型E7遺伝子は,アデノウイルスE1Aのトランザクティベーションとトランスフォーメーション機能をコードし,アデノウイルスE1Aのトランザクティベーションとトランスフォーメーションに類似しています

W C Phelps1, C L Yee, K Münger

  • 1Laboratory of Tumor Virus Biology, National Cancer Institute, Bethesda, Maryland 20892.

Cell
|May 20, 1988
PubMed
まとめ

ヒューマン・パピローマウイルス (HPV) は,アノゲニタルがんと関連しており,ほとんどの子宮頸がんではHPV-16が発見されています. HPV-16 E7タンパク質は,トランスクリプショントランザクティベーションと細胞変容機能を持つアデノウイルスE1Aと類似性を示しています.

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