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ディフタミドバイオシンセシスにおける非従来のラジカルS-アデノシルメチオニン酵素による基質依存の割れ部位選択

Min Dong1, Masaki Horitani2,3, Boris Dzikovski1

  • 1Department of Chemistry and Chemical Biology, Cornell University , Ithaca, New York 14853, United States.

Journal of the American Chemical Society
|April 7, 2017
PubMed
まとめ

ラジカルSAM酵素は,S-アデノシルメチオニン (SAM) アナログの異なる結合を割ることができます. この研究は, [4Fe-4S]クラスターが反応性を切り替えることができ,多用途の鉄硫黄クラスター化学を証明しています.

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