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Updated: Jun 15, 2026

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Published on: January 31, 2018

ガン治療のためのPARP阻害剤

Ken Y Lin1, W Lee Kraus1

  • 1University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Cell
|April 8, 2017
PubMed
まとめ

PARP阻害剤であるルカカリブは,BRCA1/ 2変異を有するがん細胞を標的とし,DNA修復を妨害する. この薬は,これらの特定の遺伝的変異を持つ再発性卵巣がんの治療に承認されています.

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