家族性遅延睡眠相障害におけるヒト日経時計遺伝子CRY1の変異
Alina Patke1, Patricia J Murphy2, Onur Emre Onat3
1Laboratory of Genetics, The Rockefeller University, New York, NY 10065, USA.
Cell
|April 8, 2017
まとめ
CRY1遺伝子の変異は 不眠症の一種である 遅延睡眠相障害 (DSPD) を引き起こします 睡眠時間が遅くなり 昼夜リズムが乱れます
科学分野:
- クロノバイオロジー
- 遺伝学
- 睡眠医学
背景:
- 人間の昼夜リズムは内在的な生物学的時計によって制御され,生理学や行動において約24時間のサイクルを保証します.
- 遅延睡眠段階障害 (DSPD) は,社会規範と睡眠タイミングの不一致を特徴とする一般的な睡眠障害である.
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