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Updated: Jul 22, 2026

Genetic Studies of Human DNA Repair Proteins Using Yeast as a Model System
14:09

Genetic Studies of Human DNA Repair Proteins Using Yeast as a Model System

Published on: March 18, 2010

酵母DNAトポイソメラーゼ変異体における転写依存DNAスーパーコイリング

S J Brill1, R Sternglanz

  • 1Department of Biochemistry, SUNY, Stony Brook 11794.

Cell
|July 29, 1988
PubMed
まとめ

イーストの研究では,DNAトポイソメラーゼIとIIはRNAポリメラーゼIIの転写に不可欠ではないが,トポイソメラーゼIは遺伝子発現中に生成されるスーパーコイルをリラックスさせるために不可欠であることを明らかにしている.

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