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Updated: May 3, 2026

Profiling of Methyltransferases and Other S-adenosyl-L-homocysteine-binding Proteins by Capture Compound Mass Spectrometry CCMS
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Profiling of Methyltransferases and Other S-adenosyl-L-homocysteine-binding Proteins by Capture Compound Mass Spectrometry CCMS

Published on: December 21, 2010

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トランス-ATポリケチド合成からC-メチルトランスファーゼのステレオ特異性の解明

Xinqiang Xie1, Chaitan Khosla2, David E Cane1

  • 1Department of Chemistry, Brown University , Box H, Providence, Rhode Island 02912-9108, United States.

Journal of the American Chemical Society
|April 22, 2017
PubMed
まとめ

S-アデノシルメチオニン (SAM) 依存C-メチルトランスファーゼは,細菌のポリケチド合成における重要なC2メチル化を触媒化する. この研究では,これらの酵素は,2-メチル-3-ケトアシル-ACPの中間物質の (2R) -ステレオアイソマーのみを生成することを明らかにした.

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Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü602809:08

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

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