胎児に対する現代の呼吸器治療の進化
Louise S Owen1, Brett J Manley2, Peter G Davis1
1Neonatal Services, The Royal Women's Hospital, Melbourne, VIC, Australia; Newborn Research Centre, The Royal Women's Hospital, Melbourne, VIC, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, VIC, Australia; Clinical Sciences, Murdoch Childrens Research Institute, Melbourne, VIC, Australia.
Lancet (London, England)
|April 27, 2017
まとめ
新生児の呼吸器のケアを 改善する必要があるのです 酸素療法や表面活性剤のような 現在の治療法には利点がありますが 結果を最適化し 肺損傷を防ぐために 更に研究が必要です 特にリスクの高い乳児の場合です
科学分野:
- 新生児医学
- 呼吸器のケア
- 小児肺科
背景:
- 胎児の早産率は 世界的に増加しており 新生児の呼吸器疾患の発生率が高くなっています
- 新生児の呼吸器疾患の治療には,酸素療法,外因的表面活性剤,呼吸器支援,産後用コルチコステロイドが含まれています.
- ブロンコ肺機能不全 (BPD) は,進歩にもかかわらず,新生児のケアにおける重要な課題です.
研究 の 目的:
- 新生児の呼吸器ケアの歴史を振り返る
- 乳児の長期的な健康状態に対する 現在の治療法の影響を分析する.
- 新生児の呼吸器支援における将来の研究方向性を特定する.
主な方法:
- 新生児の呼吸器ケアに関する過去のデータと現在の文献のレビュー
- 酸素療法,表面活性剤の置換,呼吸器のサポート方法,およびコルチコステロイドに関する有効性と論争の分析.
- ブロンコ肺機能不全の管理における課題の議論
主要な成果:
- 酸素療法の投与とモニタリングは,何十年もの使用にもかかわらず,議論の余地があります.
- 外因的表面活性剤は死亡率を大幅に低減したが,最適な投与に関するさらなる研究が必要である.
- 非侵襲的呼吸器支援は 慣例の静脈管と呼吸器を上回っています
結論:
- 新生児の呼吸器のサポートを最適化することは 早産児,特に BPDのリスクが高い赤ちゃんにとって重要です.
- 既存の治療法の使用を洗練し,新しい戦略を開発するためにさらなる研究が必要です.
- 赤ちゃんの呼吸を支えるのが目的で 肺にダメージを与えず 長期にわたって健康に悪影響を及ぼさないようにします
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