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Updated: Mar 3, 2026

Analyses of Mitochondrial Calcium Influx in Isolated Mitochondria and Cultured Cells
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Analyses of Mitochondrial Calcium Influx in Isolated Mitochondria and Cultured Cells

Published on: April 27, 2018

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ミトコンドリアのNa+/Ca2+交換器は,Ca2+のホメオスタシスと生存に不可欠である

Timothy S Luongo1, Jonathan P Lambert1, Polina Gross2

  • 1Center for Translational Medicine, Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

Nature
|April 27, 2017
PubMed
まとめ

ミトコンドリアのカルシウムエクスポーターNCLX (Slc8b1) をマウスハートで削除すると,重度の心不全と突然死が起こりました. 心臓の損傷から保護されたNCLX機能を回復し,心臓の健康における重要な役割を強調します.

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