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Updated: Mar 3, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Published on: August 4, 2019

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ヒトの多能幹細胞は,支配的な負のP53変異を繰り返し獲得し,拡大する

Florian T Merkle1,2,3,4, Sulagna Ghosh1,2,3,4, Nolan Kamitaki3,5,6

  • 1Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA.

Nature
|April 27, 2017
PubMed
まとめ

培養されたヒトの多能幹細胞 (hPS細胞) は,がんに関連したTP53変異を受け取り,成長の利点を授与することができる. これらの貴重な幹細胞の臨床使用の前に 遺伝的特徴づけが不可欠です

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