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Updated: Mar 3, 2026

Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes
09:54

Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes

Published on: September 12, 2018

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エナチオセレクティブ・トータル・シンセシス (+) - ワートマンニン

Yinliang Guo1, Tianfei Quan2, Yandong Lu1

  • 1Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Ministry of Education and Beijing National Laboratory for Molecular Science, College of Chemistry and Molecular Engineering, Peking University , Beijing 100871, China.

Journal of the American Chemical Society
|May 6, 2017
PubMed
まとめ

この研究は,PI3K阻害剤である (+) - ワートマンニンの新しい,エナンチオセレクティブ合成を詳細に説明しています. 主なステップは,Pd触媒による結合と,Friedel-Craftsアルキル化による効率的な分子構築である.

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