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Updated: Mar 3, 2026

Capturing Chromosome Conformation Across Length Scales
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コヘシン放出因子 (WAPL) はクロマチンループの拡張を制限する

Judith H I Haarhuis1, Robin H van der Weide2, Vincent A Blomen3

  • 1Division of Cell Biology, the Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.

Cell
|May 6, 2017
PubMed
まとめ

SCC2/SCC4とWAPLによって調節されるコヘシン複合体は,クロマチンループのサイズと形成を制御することによって3Dゲノムを形成します. バランスの取れた活動は,正しい染色体構造と遺伝子発現の調節を保証する.

キーワード:
CTCF についてMAU2 についてNIPBL についてSCC2 についてSCC4 についてTADs についてWAPL についてクロマチンループ結束性ループの流出

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