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関連する概念動画

Pinocytosis00:38

Pinocytosis

3.8K
Cells use energy-requiring bulk transport mechanisms to transfer large particles or large numbers of small particles into or out of the cell. The cells envelop the particles in spherical membranes called vesicles or vacuoles. Vesicles that transport material into the cell are built from the cell membrane. These vesicles encapsulate external molecules and transport them into the cell in a process called endocytosis.
Pinocytosis ("cellular drinking") is one of three main types of...
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Pinocytosis00:43

Pinocytosis

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Cells use energy-requiring bulk transport mechanisms to transfer large particles, or large amounts of small particles, into or out of the cell. The cells envelop the particles in spherical membranes called vesicles or vacuoles. Vesicles that transport material into the cell are built from the cell membrane. These vesicles encapsulate external molecules and transport them into the cell in a process called endocytosis.
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Phagocytosis00:41

Phagocytosis

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Cells pull particles inward and engulf them in spherical vesicles in an energy-requiring process called endocytosis. Phagocytosis ("cellular eating") is one of three major types of endocytosis. Cells use phagocytosis to take in large objects, such as other cells (or their debris), bacteria, and even viruses.
The objective of phagocytosis is often destruction. Cells use phagocytosis to eliminate unwelcome visitors, like pathogens (e.g., viruses and bacteria). Many immune system cells,...
7.0K
Phagocytosis00:41

Phagocytosis

89.1K
Cells pull particles inward and engulf them in spherical vesicles in an energy-requiring process called endocytosis. Phagocytosis (“cellular eating”) is one of three major types of endocytosis. Cells use phagocytosis to take in large objects—such as other cells (or their debris), bacteria, and even viruses.
89.1K
Pinching-off of Coated Vesicles01:32

Pinching-off of Coated Vesicles

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Vesicle budding is orchestrated by distinct cytosolic proteins such as adaptor proteins, coat proteins, and GTPases. To initiate vesicle budding, membrane-bending proteins containing crescent-shaped BAR domains bind to the lipid heads in the bilayer and distort the membrane to form a protein-coated vesicle bud. Adaptors proteins such as AP2 for clathrin-coated vesicles can nucleate on the deformed membrane. Finally, coat proteins such as clathrin or COPI and COPII assemble into a coat forming...
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Delivery Pathways to the Lysosome01:36

Delivery Pathways to the Lysosome

8.3K
Eukaryotic cells use different mechanisms to eliminate toxic waste obsolete and worn-out substances. Lysosomes play a pivotal role in this, and hence, these substances are carried to the lysosome from other parts of the cell and extracellular space through different pathways. The most elaborately studied pathways to the lysosome are the endocytic pathways.
Endocytosis
In endocytosis, the cell membrane takes up macromolecules and particles from the surrounding medium. Clathrin-mediated...
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関連する実験動画

Updated: Nov 5, 2025

Automated Imaging and Analysis for the Quantification of Fluorescently Labeled Macropinosomes
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Automated Imaging and Analysis for the Quantification of Fluorescently Labeled Macropinosomes

Published on: August 24, 2021

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スナップショット:マクロピノサイトーシス

Pedro E Marques1, Sergio Grinstein2, Spencer A Freeman1

  • 1Program in Cell Biology, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, 686 Bay Street, 19-9800, Toronto, ON M5G 0A4, Canada.

Cell
|May 6, 2017
PubMed
まとめ
この要約は機械生成です。

マクロピノサイトーシス (細胞の大量流体吸収) は免疫監視に不可欠です. この過程は感染と癌の進行にも貢献します

さらに関連する動画

Measuring the pH, Redox Chemistries, and Degradative Capacity of Macropinosomes using Dual-Fluorophore Ratiometric Microscopy
07:31

Measuring the pH, Redox Chemistries, and Degradative Capacity of Macropinosomes using Dual-Fluorophore Ratiometric Microscopy

Published on: August 19, 2021

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Visualizing Membrane Ruffle Formation using Scanning Electron Microscopy
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Visualizing Membrane Ruffle Formation using Scanning Electron Microscopy

Published on: May 27, 2021

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関連する実験動画

Last Updated: Nov 5, 2025

Automated Imaging and Analysis for the Quantification of Fluorescently Labeled Macropinosomes
11:01

Automated Imaging and Analysis for the Quantification of Fluorescently Labeled Macropinosomes

Published on: August 24, 2021

3.0K
Measuring the pH, Redox Chemistries, and Degradative Capacity of Macropinosomes using Dual-Fluorophore Ratiometric Microscopy
07:31

Measuring the pH, Redox Chemistries, and Degradative Capacity of Macropinosomes using Dual-Fluorophore Ratiometric Microscopy

Published on: August 19, 2021

2.6K
Visualizing Membrane Ruffle Formation using Scanning Electron Microscopy
08:05

Visualizing Membrane Ruffle Formation using Scanning Electron Microscopy

Published on: May 27, 2021

2.8K

科学分野:

  • 細胞生物学
  • 免疫学
  • 病理学について

背景:

  • マクロピノサイトーシスは,細胞外液の大量吸収を伴う細胞内のプロセスである.
  • このメカニズムは免疫細胞機能を含む様々な生理学的プロセスにおいて重要な役割を果たします.

研究 の 目的:

  • マクロピノサイトーシスの生理学的役割の概要を説明する.
  • 病状におけるマクロピノサイトーシスの病原性貢献を調査する.

主な方法:

  • マクロピノサイトーシスの文献レビュー
  • 免疫監視におけるマクロピノサイトーシスの分析
  • 感染症と癌におけるマクロピノサイトーシスの調査

主要な成果:

  • マクロピノサイトーシスは,抗原を提示する細胞による免疫監視に不可欠です.
  • 異常なマクロピノサイトーシスは癌細胞の増殖と生存に関与している.
  • マクロピノサイトーシスは 病原体によって利用され 感染を促進します

結論:

  • マクロピノサイトーシスは健康と病気の2つの役割を担う 基本的な細胞プロセスです
  • マクロピノサイトーシスの理解は 感染症や癌の治療対象となる可能性があります