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Updated: Mar 2, 2026

G Protein-selective GPCR Conformations Measured Using FRET Sensors in a Live Cell Suspension Fluorometer Assay
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G Protein-selective GPCR Conformations Measured Using FRET Sensors in a Live Cell Suspension Fluorometer Assay

Published on: September 10, 2016

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GPCR-Gタンパク質結合の選択性決定因子

Tilman Flock1,2, Alexander S Hauser3, Nadia Lund3

  • 1MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.

Nature
|May 11, 2017
PubMed
まとめ

研究者はGタンパク質に "選択性バーコード"を発見し,受容体はそれを結合して活性化します. この分子パターンは,異なる受容体が特定の生理学的反応のために特定のGタンパク質結合を達成する方法を説明します.

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