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Updated: Jun 8, 2026

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins
16:10

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

Published on: March 22, 2012

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T細胞によるリガンド検出の際のダイナミックなマイクロビラー検索と安定化を視覚化

En Cai1, Kyle Marchuk1,2, Peter Beemiller1

  • 1Department of Pathology, University of California, San Francisco, CA 94143, USA.

Science (New York, N.Y.)
|May 13, 2017
PubMed
まとめ

T細胞はフラクタルマイクロビルを迅速な免疫監視のために使用し,ペプチドに負荷された主要な組織適合性複合体 (pMHCs) を検出すると安定させ,細胞相互作用の間に感受性を高めます.

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Real-time Live Imaging of T-cell Signaling Complex Formation10:31

Real-time Live Imaging of T-cell Signaling Complex Formation

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Visualizing Surface T-Cell Receptor Dynamics Four-Dimensionally Using Lattice Light-Sheet Microscopy

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関連する概念動画

Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...