関連する実験動画

Updated: Mar 2, 2026

Visualizing Clathrin-mediated Endocytosis of G Protein-coupled Receptors at Single-event Resolution via TIRF Microscopy
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Visualizing Clathrin-mediated Endocytosis of G Protein-coupled Receptors at Single-event Resolution via TIRF Microscopy

Published on: October 20, 2014

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レチキュロン3依存型ER-PM接触部位はEGFRの非クラトリン内分泌を制御する

Giusi Caldieri1, Elisa Barbieri1, Gilda Nappo1

  • 1Fondazione Istituto FIRC di Oncologia Molecolare (IFOM), Via Adamello 16, 20139 Milan, Italy.

Science (New York, N.Y.)
|May 13, 2017
PubMed
まとめ

皮質成長因子受容体 (EGFR) は,レチクロン3 (RTN3) とカルシウムシグナル伝達を含む非クラトリン内細胞経路を使用します. このプロセスは,受容体分解と信号衰弱を調節するために,プラズマ膜-ER接触部位を使用します.

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