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Updated: Mar 2, 2026

ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast
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人間 の スプライソーム の 原子 構造

Xiaofeng Zhang1, Chuangye Yan1, Jing Hang1

  • 1Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

Cell
|May 16, 2017
PubMed
まとめ

エクソン結合前にヒトスプレイスソームC*複合体の冷凍電子顕微鏡構造を決定した. これは,Prp17とSlu7のようなスプライシング因子と,イントロンラリアートが,この重要な遺伝子発現のステップを 促進するためにどのように相互作用するかを明らかにします.

キーワード:
C (() コンプレックスEJC について原子構造クリオ・エムエクソン・ジャンクション・コンプレックスエクソン結合ヒトのスプライソームmRNA前スプライシングステップ2の因子ステップII活性化スプリセソーム

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