調

Lee A Solomon1, Jacob B Kronenberg2, H Christopher Fry1

  • 1Argonne National Laboratory , 9700 South Cass Avenue, Argonne, Illinois 60439, United States.

まとめ

研究者は,自己組織化ペプチド材料にヘム-Bを組み込み,触媒作用を強めた. ヘム反応性とペロキシダース活性がペプチド配列と物質構造 (ミセルと繊維) に依存することを発見した.

関連する概念動画

Protein Folding01:25

Protein Folding

Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
11.9K
Protein Folding01:22

Protein Folding

Overview
129.0K
Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein.
The...
20.5K
Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

15.2K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
9.1K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

2.7K