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Updated: Mar 2, 2026

Mapping Dysfunctional Protein-Protein Interactions in Disease
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Mapping Dysfunctional Protein-Protein Interactions in Disease

Published on: October 24, 2025

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ヒトのインタラクタームの構造は,タンパク質コミュニティと疾患ネットワークを定義する

Edward L Huttlin1, Raphael J Bruckner1, Joao A Paulo1

  • 1Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|May 18, 2017
PubMed
まとめ

BioPlex 2.0はヒトのタンパク質の相互作用をマップし 56,000以上の関連や 1,300のタンパク質コミュニティを明らかにしています この大規模なプロテオームマップは 遺伝子を細胞の機能と 2,000以上の病気と結びつけています

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