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Updated: Mar 2, 2026

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
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Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions

Published on: June 28, 2018

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クリプティックプロモーターでの乱交的活性化をブロックすると,細胞タイプ特有の遺伝子発現を誘導する

Jongmin Kim1,2, Chenggang Lu2, Shrividhya Srinivasan2

  • 1Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305-5329, USA.

Science (New York, N.Y.)
|May 20, 2017
PubMed
まとめ

亜鉛指タンパク質であるクンガン (Kmg) とdMi-2は,ドロソフィラの雄性生殖細胞における体内遺伝子転写を阻害する. これは,望ましくないプロモーターの活動をブロックすることによって,開発中の適切な遺伝子活性化を保証します.

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