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Updated: Mar 2, 2026

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries

Published on: March 31, 2019

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CTCFの標的的劣化により,染色体領域の局所的な分離がゲノム分割から分離される

Elphège P Nora1, Anton Goloborodko2, Anne-Laure Valton3

  • 1Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, CA 94158, USA.

Cell
|May 20, 2017
PubMed
まとめ

転写因子CTCFは哺乳類の染色体折り畳みとトポロジカルアソシエイトドメイン (TAD) の組織化に不可欠である. CTCF について

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