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不一致修復欠陥は,固体腫瘍のPD-1阻害に対する反応を予測する

Dung T Le1,2,3, Jennifer N Durham1,2,3, Kellie N Smith1,3

  • 1Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD 21287, USA.

Science (New York, N.Y.)
|June 10, 2017
PubMed
まとめ

多くの変異を持つ不一致修復欠陥がんは,プログラムされた死亡受容体-1 (PD-1) 阻害に対する高い反応率を示しています. この免疫療法のアプローチは様々ながんに有効で 患者さんには持続的な利点をもたらします

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