方向性分子運動のオーケストラ化:棒状のホストの運動制御された超分子経路
Xiang Wang1, Barbara Wicher1, Yann Ferrand1
1CBMN Laboratory, University of Bordeaux, CNRS, IPB, Institut Européen de Chimie Biologie, 2 rue Escarpit 33607 Pessac, France.
Journal of the American Chemical Society
|June 14, 2017
まとめ
研究者は,オリゴカルバマートゲストのための二重の螺旋状ホストを作成するために,自己組み立て オリゴアミドを設計しました. これらのフォルダキサン複合体は制御された分子運動と複雑な超分子現象を示し,ダイナミックな分子システムへの洞察を提供します.
科学分野:
- 超分子化学
- 有機化学
- 材料科学
背景:
- 芳香性オリゴアミドは複雑な構造に自己組み立てることができる.
- 制御可能なダイナミクスを持つホスト-ゲストシステムの設計は,超分子化学の重要な課題です.
研究 の 目的:
- 線形オリゴカルバメートゲストを結合できる 双回螺旋ホストの設計と合成
- 螺旋主体内のゲストスレッド,スライディング,解離の運動を調査する.
- 複雑な超分子現象をプログラムする フォルダキサンの可能性を証明する
主な方法:
- 芳香性オリゴアミドホストと機能化されたオリゴカルバマートゲストの設計と合成.
- 核磁共振 (NMR) とX線結晶学を用いたフォルダキサン複合体の形成の特徴化.
- ゲストのスレッド,スライディング,解離のダイナミクスを監視するためにH NMRを用いた運動研究.
主要な成果:
- オリゴアミド宿主とオリゴカルバマート宿主との間に螺旋状のシドオロタキサン複合体 (フォルダキサン) が形成される.
- 中間結合と間隔器に沿って急速な滑りを含む宿主滑り中の複雑な運動現象の観察.
- 運動障壁が超分子軌道を制御し,解離再結合のステップを意図的に統合することを示した.
- 急速なスライディングプロセス (時間) と,より遅いヘリックス解き回しイベント (日) を区別する.
結論:
- フォルダキサンは,超分子システムにおける分子運動の研究と制御のための多用途のプラットフォームを提供します.
- 個々のステップの運動は 超分子事件の複雑な配列を設計するために調整できます
- この研究は,ダイナミックな分子構造と機能的な超分子材料の設計原理を進めている.
関連する概念動画
03:07Kinetic Molecular Theory: Molecular Velocities, Temperature, and Kinetic Energy
30.0K
The kinetic molecular theory qualitatively explains the behaviors described by the various gas laws. The postulates of this theory may be applied in a more quantitative fashion to derive these individual laws.
30.0K
02:43Basic Postulates of Kinetic Molecular Theory: Particle Size, Energy, and Collision
38.0K
The ideal-gas equation, which is empirical, describes the behavior of gases by establishing relationships between their macroscopic properties. For example, Charles’ law states that volume and temperature are directly related. Gases, therefore, expand when heated at constant pressure. Although gas laws explain how the macroscopic properties change relative to one another, it does not explain the rationale behind it.
38.0K
01:21Molecular Kinetic Energy
5.7K
The word "gas" comes from the Flemish word meaning "chaos," first used to describe vapors by the chemist J. B. van Helmont. Consider a container filled with gas, with a continuous and random motion of molecules. During collisions, the velocity component parallel to the wall is unchanged, and the component perpendicular to the wall reverses direction but does not change in magnitude. If the molecule’s velocity changes in the x-direction, then its momentum is changed.
5.7K
02:34Kinetic Molecular Theory and Gas Laws Explain Properties of Gas Molecules
37.6K
The test of the kinetic molecular theory (KMT) and its postulates is its ability to explain and describe the behavior of a gas. The various gas laws (Boyle’s, Charles’s, Gay-Lussac’s, Avogadro’s, and Dalton’s laws) can be derived from the assumptions of the KMT, which have led chemists to believe that the assumptions of the theory accurately represent the properties of gas molecules.
37.6K
01:11Direct Motor Pathways
4.6K
The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
4.6K
00:23Kinetic Energy
43.6K
Kinetic energy is the ability of an object in motion to do work or enact change. It can take on many forms. For instance, water flowing down a waterfall has kinetic energy. In biological systems, particles of light travel and are absorbed by plants to create chemical energy. Animals consume the chemical energy and give off molecules that carry their scent through the air. They also generate kinetic energy when they run away from predators. Entire systems also possess kinetic energy, like the...
43.6K