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RagD GTPaseの転写活性化により,mTORC1が制御され,がんの成長が促進される

Chiara Di Malta1, Diletta Siciliano1, Alessia Calcagni1

  • 1Telethon Institute of Genetics and Medicine (TIGEM), Via Campi Flegrei 34, 80078 Pozzuoli, Naples, Italy.

Science (New York, N.Y.)
|June 17, 2017
PubMed
まとめ

リソソーム機能の主調節体,MiT/TFE転写因子,RagDを調節することによってmTORC1活動を制御する. この経路は 栄養素の適応に不可欠であり 癌細胞の成長を促します

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