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Updated: Feb 28, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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ドミノ・ダイレクト・アリレーションとクロス・アルドールは,拡張された多循環型π・スキャフォールドの急速な構築のために

Andrea Nitti1, Gabriele Bianchi2, Riccardo Po2

  • 1Department of Chemistry and INSTM Research Unit, University of Pavia , Viale Taramelli 10, 27100 Pavia, Italy.

Journal of the American Chemical Society
|June 17, 2017
PubMed
まとめ

π結合物質のための5つ組の芳香性ヘテロサイクルを合成することは困難です. この研究は,迅速なチオフェンとフラン材料の構築のための効率的でスケーラブルな1ポットクロスアルドール直接アリレーションを導入します.

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