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Updated: Feb 28, 2026

Rapid, Seamless Generation of Recombinant Poxviruses using Host Range and Visual Selection
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トランス・キングダム・ミミクリーは,ポックスウイルスキナーゼによるリボソームのカスタマイズに基礎を置いている

Sujata Jha1, Madeline G Rollins1, Gabriele Fuchs2

  • 1Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

Nature
|June 22, 2017
PubMed
まとめ

ポックスウイルスは,RACK1タンパク質をリン酸化して宿主リボソームを乗っ取り,ウイルスのRNAの翻訳を好むようにその構造を変更します. このトランス・キングダム・ミミクリーは,ウイルスが複製のためにRNAポリメラーゼのエラーを利用することを可能にします.

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