Haoliang Chen1, Xiujing He1, Meihui Su1

  • 1State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Functional Polymer Materials, Ministry of Education, College of Pharmacy, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Nankai University , Tianjin 300071, P. R. China.

まとめ

研究者らは,ボロン二酸化メタン (BODIPY) 染料を用いた高光プローブを作成するための新しい戦略を開発しました. このアプローチにより,様々な分析物質を検出し,生きている細胞のイメージングを行うための多用途のバイオサンブの開発が可能になります.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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