菜食主義ヒンドゥー教のコミュニティにおけるメガロブラスティック貧血
Lancet (London, England)
|November 23, 1985
まとめ
栄養上のコバラミン欠乏症は,インドのベジタリアンに多く見られ,メガロブラスティック貧血やその他の健康問題につながります. この集団では悪性貧血も頻繁に発生します.
科学分野:
- 血液学 ヘマトロジ
- 栄養科学とは,栄養科学である.
- 胃腸内科 胃腸内科
背景:
- 主に生涯ベジタリアンであったインド人の患者におけるメガロブラスティック血液形成が調査されました.
- この人口集団における栄養不足と関連する状態のスペクトルを理解することは極めて重要です.
研究 の 目的:
- インドのベジタリアンにおけるメガロブラスティック・ヘモポエーシスの原因を特定する.
- コバラミン欠乏症,葉酸欠乏症,悪性貧血,および関連する合併症の流行を評価する.
主な方法:
- メガロブラスティック・ヘモポエシスと診断された138人のインド人の患者の遡及的分析.
- 特定の診断と併存状態を特定するために,臨床および検査データのレビュー.
主要な成果:
- 栄養的なコバラミン欠乏症は95人の患者で診断され,20人の患者で悪性貧血が診断されました.
- 葉酸欠乏症は4人の患者しかありませんでした. 3分の1の患者に腸内マラボソルプションが認められた.
- 骨粗鬆症 (20人の患者) と鉄欠乏症 (87人の患者) の有意な割合が観察されました. 結核は17人の患者で診断されました.
結論:
- 栄養上のコバラミン欠乏症は,インドのベジタリアンにおけるメガロブラスティック・ヘモポエーシスの主要な原因である.
- コバラミン欠乏症は,腸内マラ吸収や免疫機能低下などの合併症を悪化させる可能性があります.
- インド人の患者に発症する悪性貧血の発生率は,白人の集団と比較できます.
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