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Updated: Feb 27, 2026

Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function
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Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function

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プロテイン・レドックス・センターのエンタルピック/エントロピックパラメータを電子分割関数操作で調節する

Damian Alvarez-Paggi1, Ulises A Zitare1, Jonathan Szuster1

  • 1Instituto de Química Física de los Materiales, Medio Ambiente y Energía (INQUIMAE), Departamento de Química Inorgánica, Analítica y Química Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires and CONICET ,1428 Buenos Aires, Argentina.

Journal of the American Chemical Society
|July 1, 2017
PubMed
まとめ

研究者は,シトクロームc酸化酵素における銅-A (CuA) リドックスセンターの分割関数 (Q) を調整した. このチューニングは電子状態と静電環境を変化させることで リドックスポテンシャルを調節し,重要な熱力学的相関を明らかにした.

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