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Updated: Feb 27, 2026

RNA Next-Generation Sequencing and a Bioinformatics Pipeline to Identify Expressed LINE-1s at the Locus-Specific Level
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RNA Next-Generation Sequencing and a Bioinformatics Pipeline to Identify Expressed LINE-1s at the Locus-Specific Level

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LTR-レトロトランスポソン tRNA 派生小RNAによる制御

Andrea J Schorn1, Michael J Gutbrod2, Chantal LeBlanc3

  • 1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

Cell
|July 1, 2017
PubMed
まとめ

tRNA由来断片 (tRFs) と呼ばれる小さなRNAは,その複製機構を標的として,内生レトロウイルス (ERVs) を抑制する. この発見により 細胞内のトランポゾン活性を制御する 新しいメカニズムが明らかになりました

キーワード:
LTR逆転移動性についてエピジェネティック・リプログラミングマウス内生レトロウイルス小型RNAtRNA 断片トランポゾン制御

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