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Updated: Feb 27, 2026

Generation of Cancer Cell Clones to Visualize Telomeric Repeat-containing RNA TERRA Expressed from a Single Telomere in Living Cells
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Generation of Cancer Cell Clones to Visualize Telomeric Repeat-containing RNA TERRA Expressed from a Single Telomere in Living Cells

Published on: January 17, 2019

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TERRA RNAはATRXとテロメアを保護する

Hsueh-Ping Chu1, Catherine Cifuentes-Rojas1, Barry Kesner1

  • 1Howard Hughes Medical Institute, Boston, MA 02114, USA; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02114, USA.

Cell
|July 1, 2017
PubMed
まとめ

長い非コードRNA TERRAは遺伝子発現を調節し,テロメアの安定性を維持する. ATRXの結合を制限することで,テロメアの機能障害を予防します.

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