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シャガス病
José A Pérez-Molina1, Israel Molina2
1National Referral Centre for Tropical Diseases, Infectious Diseases Department, Hospital Universitario Ramón y Cajal, Insituto Ramón y Cajal de Investgación Sanitaria, Madrid, Spain.
Lancet (London, England)
|July 5, 2017
PubMed で要約を見る
まとめ
チャガス病は トライパノソーマ クルージによって引き起こされ,アメリカ大陸では依然として重大な健康問題です. この複雑な寄生虫感染の管理には 診断,治療,制御戦略の改善が不可欠です
科学分野:
- 軽視された熱帯病
- 寄生虫感染
- アメリカン・トリパノソミアシス
背景:
- チャガスの病は,アメリカ大陸に固有の動物性寄生虫病であり,トライパノソーマ・クルージによって引き起こされます.
- 移住によって シャガスの病気が 世界中に広がっています
- 慢性的なシャガスの病は 患者の30~40%で 心筋病や大腸のような 深刻な合併症を引き起こします
研究 の 目的:
- シャーガス病の管理に伴う課題を強調する
- 制御,診断,治療における進歩の必要性を強調する.
- 進化する患者集団と 複雑なニーズを強調するためです
主な方法:
- シャガスの病気に関する現在の知識と課題のレビュー
- 既存の診断・治療・予測ツールの限界を分析する.
- 流行病学的状況と患者の人口統計の変化に関する議論
主要な成果:
- 百年以上に渡る研究にもかかわらず シャガスの病気の制御と治療には 満たされていない大きな需要が残っています
- 現在の治療薬の有効性と耐容性は最適ではない.
- 感染した集団はますます複雑になり,高齢者や免疫力が低下した個人を含む.
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