左心室 補助 装置 の 機能 障害: ポンプ だけ で は ない
Robert L Kormos1, Michael McCall2, Andrew Althouse2
1From Heart and Vascular Institute (R.L.K., A.A., L.L., C.S., J.J.T.); Artificial Heart Program (M.C., R.S., K.L., N.K., E.D.), University of Pittsburgh Medical Center, PA; Department of Bioengineering, Rochester Institute of Technology, NY (M.A.K.); and Department of Engineering, University of Pittsburgh, PA (J.A.Z.). kormosrl@upmc.edu.
Circulation
|July 5, 2017
まとめ
左心室補助器 (LVAD) の機能不全は,ポンプ血栓症を超えて,コントローラと周辺器の故障がより一般的です. 異なるLVADモデルは,部品の故障率が異なるため,デバイスの信頼性に影響します.
科学分野:
- 心臓病科
- 生物医学工学
- 医療機器
背景:
- 左心室補助器 (LVAD) の機能不全は,しばしばポンプ血栓症に起因する.
- しかし,LVADはポンプ,ドライブライン,周辺機器を含んでおり,すべて故障に敏感です.
研究 の 目的:
- 回転型LVADにおける装置障害 (DM) の発生率と種類を分析する.
- 異なるコンポーネントとLVADモデルの故障率を比較する.
主な方法:
- 108個のハートメイトII (HMII) と105個のハートウェアVAD (HVAD) のプロスペクティブデータを検討した.
- 装置の故障はコンポーネント (コントローラ,周辺機器,ポンプ/ドライブライン) によって分類され,Coxの比例的な危険モデルを使用して分析された.
- 機能不全率は1000患者日あたりで計算された.
主要な成果:
- コントローラー (30%),バッテリー (19%),患者用ケーブル (14%) の故障はポンプの故障より頻繁でした.
- Heartmate IIデバイスは,HeartWare VAD (3. 06/ 1000患者日) よりも,全体的な障害率 (3. 73/ 1000患者日) が高かった.
- ハートメイトIIはポンプ特異的および外周機能障害が増加し,ハートウェアVADは優れたドライブラインの完全性を示しました.
結論:
- LVAD装置の故障は,以前強調したよりも幅広い構成要素の故障を網羅しています.
- LVADのタイプは,デバイスの故障の発生率と性質に大きな影響を与えます.
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