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Updated: May 10, 2026

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry
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Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry

Published on: July 20, 2016

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効率的なサイト固有の生物結合によって可能となる機械的に不安定なα-ヘリクルスタンパク質の急速な特徴化

Robert Walder1, Marc-André LeBlanc, William J Van Patten1

  • 1JILA, National Institute of Standards and Technology and University of Colorado , Boulder, Colorado 80309, United States.

Journal of the American Chemical Society
|July 6, 2017
PubMed
まとめ

この研究は,原子力顕微鏡 (AFM) 単分子力スペクトロスコピー (SMFS) の新しい方法を提示し,データ品質とスループットを大幅に向上させます. 強化された技術は,機械的に不安定なタンパク質α3Dを含む多様な生物分子機械的性質の急速な特徴付けを可能にします.

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