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Updated: Feb 27, 2026

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy
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パーソナライズされたRNAミュータノームワクチンは,がんに対するポリスペシフィックな治療免疫を動員する

Ugur Sahin1,2,3, Evelyna Derhovanessian1, Matthias Miller1

  • 1Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, 55131 Mainz, Germany.

Nature
|July 6, 2017
PubMed
まとめ

ガン変異を標的とした個別化されたRNAワクチンは,メラノーマ患者のT細胞を成功裏に活性化させました. このパーソナライズされた免疫療法のアプローチは,転移を大幅に減らし,進行のない生存率を向上させ,がん治療の新たな経路を示しました.

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