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脂質過酸化酵素経路に対するがん細胞の耐性状態の依存性

Vasanthi S Viswanathan1, Matthew J Ryan1, Harshil D Dhruv2

  • 1Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, USA.

Nature
|July 6, 2017
PubMed
まとめ

がん細胞はフェロプトーシスを回避するために脂質過酸化経路に依存する高メゼンキマ状態を通して治療抵抗性を発達させる. この経路を阻害すると 抵抗性の高い癌細胞は 細胞死に易くなります

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