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Updated: Feb 27, 2026

Do's and Don'ts of Cryo-electron Microscopy: A Primer on Sample Preparation and High Quality Data Collection for Macromolecular 3D Reconstruction
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Do's and Don'ts of Cryo-electron Microscopy: A Primer on Sample Preparation and High Quality Data Collection for Macromolecular 3D Reconstruction

Published on: January 9, 2015

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タンパク質伝導 ERAD チャンネル Hrd1 と Hrd3 の複合体における Cryo-EM 構造

Stefan Schoebel1, Wei Mi2, Alexander Stein3

  • 1Howard Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA.

Nature
|July 7, 2017
PubMed
まとめ

この研究は,Hrd1が内プラズマ網膜にチャネルを形成し,内プラズマ網膜関連タンパク質分解 (ERAD) 経路を通じた分解のための誤った折りたたみのタンパク質の逆転移を促進することを明らかにしています.

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Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy08:27

Expression and Purification of the Human Lipid-sensitive Cation Channel TRPC3 for Structural Determination by Single-particle Cryo-electron Microscopy

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High-resolution Single Particle Analysis from Electron Cryo-microscopy Images Using SPHIRE13:28

High-resolution Single Particle Analysis from Electron Cryo-microscopy Images Using SPHIRE

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