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Updated: Feb 27, 2026

Modeling an Enzyme Active Site using Molecular Visualization Freeware
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Modeling an Enzyme Active Site using Molecular Visualization Freeware

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酵素アーキテクチャ:トリオセフォスファートイソメラーゼによる触媒における水害性クランプの動作をモデル化

Yashraj S Kulkarni1, Qinghua Liao1, Dušan Petrović2

  • 1Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University , BMC Box 596, Uppsala S-751 24, Sweden.

Journal of the American Chemical Society
|July 8, 2017
PubMed
まとめ

トリオフォスファートイソメラーゼ (TIM) は,触媒を強化するために,水害性クランプを使用します. このクランプは,酵素活性に不可欠な基板の脱プロトン化のためのギブスの自由エネルギーを最小限にします.

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