関連する実験動画

Updated: Jun 25, 2026

Isolation of Precursor B-cell Subsets from Umbilical Cord Blood
14:06

Isolation of Precursor B-cell Subsets from Umbilical Cord Blood

Published on: April 16, 2013

ネズミの髄から2つの初期のBリンパ球の祖先を分離した:コミットされたpre-pre-B細胞とクローノジェニックのThy-1-lo血液生成性幹細胞

C E Muller-Sieburg, C A Whitlock, I L Weissman

    Cell
    |February 28, 1986
    PubMed
    まとめ

    研究者らは,骨髄における2つの新しい早期Bリンパ球前駆体集団を特定した. 1つの集団であるThy-1+細胞は,多能性の血液形成性幹細胞の源として有望であることを示しています.

    さらに関連する動画

    Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays08:56

    Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays

    Published on: June 9, 2015

    Flow Cytometric Characterization of Murine B Cell Development08:25

    Flow Cytometric Characterization of Murine B Cell Development

    Published on: January 22, 2021

    関連する概念動画

    Lineage Commitment01:21

    Lineage Commitment

    Commitment is the  process whereby stem cells:
    Production of Formed Elements01:34

    Production of Formed Elements

    Hemangioblasts are multipotent stem cells originating from the mesoderm. They give rise to hematopoietic stem cells (HSCs), which undergo hematopoiesis to produce all the formed elements of blood. This process is regulated by a complex network of hematopoietic growth factors, including transcription factors, growth factors, and cytokines. These factors stimulate the HSCs to divide and differentiate, though some HSCs remain undifferentiated to maintain a self-renewing pool.
    Most HSCs commit to...
    Primary Lymphoid Organs01:16

    Primary Lymphoid Organs

    Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
    The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
    Cells of the Adaptive Immune Response01:23

    Cells of the Adaptive Immune Response

    The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
    B Cell Activation and Differentiation01:24

    B Cell Activation and Differentiation

    The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
    When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...