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Updated: Feb 27, 2026

Nanomanipulation of Single RNA Molecules by Optical Tweezers
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小分子認識はDNA折り畳みとハンマーヘッドリボ酵素触媒における二次および三次相互作用を誘発する

Jie Mao1, Chris DeSantis1, Dennis Bong1

  • 1Department of Chemistry and Biochemistry, The Ohio State University , 100 West 18th Avenue, Columbus, Ohio 43210, United States.

Journal of the American Chemical Society
|July 11, 2017
PubMed
まとめ

トリス (((2-アミノエチル) アミン (トレン) から派生した新しい合成スキャフォードは,特定のDNA/RNA構造を標的にし,再折りたたむことができます. これらの化合物は機能的なスイッチとして作用し,新しいアロステルリボスイッチと小分子核酸複合体の設計を可能にします.

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