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Updated: Feb 27, 2026

Transmembrane Domain Oligomerization Propensity determined by ToxR Assay
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背骨の水素結合の強さは,トランスメブランヘリックスで大きく異なる

Zheng Cao1, James M Hutchison2, Charles R Sanders2

  • 1Department of Chemistry and Biochemistry, UCLA-DOE Institute, Molecular Biology Institute, University of California , Los Angeles, California 90095, United States.

Journal of the American Chemical Society
|July 11, 2017
PubMed
まとめ

研究者は,アミロイド前駆体タンパク質 (APP) のトランスメブランヘリックスにおける骨幹の水素結合強さを測定した. 分裂部位の近くに弱い結合があり,酵素処理のためのタンパク質アクセシビリティの役割を示唆しています.

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