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リーシュマニア・ドノヴァーニ (Leishmania donovani):3人の免疫低下患者の進行性疾患に関連した機会性微生物
Lancet (London, England)
|March 22, 1986
まとめ
Leishmania donovaniは,免疫力が低下した個人に重篤で進行する病気を引き起こす可能性があります. この寄生虫感染であるリーシュマニア症は,暴露から数年後に再発することがあり,その好機的性質を強調しています.
科学分野:
- 感染症 感染症は感染症です.
- 免疫学 免疫学とは
- 寄生虫学とは,寄生虫学である.
背景:
- リーシュマニア・ドノヴァニ (Leishmania donovani) は,内臓のリーシュマニア症を引き起こすことが知られている寄生虫です.
- 免疫力が低下した宿主は,機会性感染症に敏感です.
- Leishmania donovaniに以前に感染した人は,永続的な免疫を与えられない可能性があります.
研究 の 目的:
- 免疫不全の宿主における進行性ライシュマニア・ドノヴァニ病の症例を記述する.
- Leishmania donovani.の長期的な生存の可能性を強調する.
主な方法:
- 進行中のリーシュマニア症の3人の患者のケースレポート分析.
- 免疫抑制療法および併存状態を含む患者の病歴のレビュー.
主要な成果:
- 免疫力が低下した3人の患者は,進行するリーシュマニア症を発症した.
- 患者は,コルチコステロイド,サイクロフォスファミド,クロラムフェニコルを含む治療を受けている.
- 2つの症例は,数年前に流行地域を離れた個人を含むもので,長期の寄生虫生存を示唆しています.
結論:
- Leishmania donovaniは,免疫不全の宿主において進行性疾患を引き起こす可能性があります.
- 寄生虫は宿主の中で長期間休眠状態に留まることがあります.
- リーシュマニア・ドノヴァニは,好機的病原体として認識されるべきである.
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