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Updated: Feb 26, 2026

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
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Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

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大規模な並列設計,合成,試験を用いたタンパク質の折り畳みのグローバル分析

Gabriel J Rocklin1, Tamuka M Chidyausiku1,2, Inna Goreshnik1

  • 1Department of Biochemistry and Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.

Science (New York, N.Y.)
|July 15, 2017
PubMed
まとめ

研究者は1万5千以上の新しいタンパク質を設計し テストし 配列がタンパク質の折り畳みと安定性を 決定する仕組みを理解しました このデータベースのアプローチは タンパク質設計の成功率を大幅に改善しました

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