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Updated: Feb 26, 2026

Isolation and Characterization of RNA-Containing Exosomes
09:43

Isolation and Characterization of RNA-Containing Exosomes

Published on: January 9, 2012

100.6K

エクソソームRNA非遮蔽カップル 腫瘍におけるパターン認識受容体シグナルへのストロマル活性化

Barzin Y Nabet1, Yu Qiu1, Jacob E Shabason1

  • 1Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Cell
|July 15, 2017
PubMed
まとめ

乳がん細胞はストロマ NOTCH-MYCを誘発し,RNA RN7SL1を増加させる. エキソソムの非遮蔽RN7SL1は,パターン認識受容体 (PRRs) を活性化することによって,炎症,腫瘍の成長,転移,および治療抵抗を促進する.

キーワード:
RIG-IRNA結合タンパク質乳がんエクソソームフィブロブラストパターン認識受容器放射線療法シールドストロマル活性化腫瘍の微小環境

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